THE BASIC PRINCIPLES OF FENTANYL AND XYLAZINE

ritlecitinib will increase the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Ritlecitinib inhibits CYP3A4 substrates; coadministration raises AUC and peak plasma concentration delicate substrates, which may enhance risk of adverse reactions.Concomitant utilization of fentanyl